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Cover image: Copyright © 2000, Nestle Purina Company, St. Louis, MO. Photographs of littermate, pair-fed, aging, Labrador Retrievers taken during a long-term, diet-restriction study during which their antioxidant status was investigated (See Stowe et al., this issue, pages 1844-1848). The left panel shows one pair at 6 y of age; the right shows the same pair at 10 y of age. In each panel, the diet-restricted dog is on the left and the control-fed dog is on the right.