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Cover images: Illustration 1 (top): Copyright © 2005, W. G. Bergen. Intracellular pathways of fatty acid carbon precursors for animals that are either glucose or acetic acid utilizers for de novo fatty acid synthesis. See Bergen and Mersmann, J. Nutr. 135: 2499–2502, 2005; Illustration 2 (middle): Copyright ©2005, D. B. Jump. (n-3) PUFA affect multiple mechanisms to control SREBP-1c nuclear abundance. See Jump et al., J. Nutr. 135: 2503–2506, 2005; Illustration 3 (bottom): Copyright © 2005, J. A. Foran. Benefit-risk ratios for farmed and wild salmon. See Foran et al., J. Nutr. 135: 2639Ð2643, 2005.