![[Feedback]](/icons/banner/feedbackACT.gif){kind=icon}
![[For Subscribers]](/icons/banner/subscriberACT.gif){kind=icon}
![[Archive]](/icons/banner/archiveACT.gif){kind=icon}
![[Search]](/icons/banner/searchACT.gif){kind=icon}
![[Contents]](/icons/banner/tocACT.gif){kind=icon}
|
|
|
|
|
||
Program in International Nutrition, Department of Nutrition, University of California, Davis and * ICDDR,B: Centre for Health and Population Research, Dhaka, Bangladesh
2To whom correspondence should be addressed. E-mail: kgdewey{at}ucdavis.edu.
 |
ABSTRACT |
|---|
 TOP ABSTRACT SUBJECTS AND METHODSRESULTSDISCUSSIONLITERATURE CITED |
|---|
KEY WORDS: • infant dietary intake • Bangladesh • breast-feeding • complementary food • malnutrition
The rates of childhood malnutrition in rural Bangladesh are among the highest in the world: 
55% of children < 5 y old are stunted and 18% have low weight-for-height (1). Among children 6–11 mo and 12–23 mo old, the prevalence of anemia (hemoglobin < 110 g/L) is 78 and 64%, respectively (2); 11% of children die before reaching the age of 5 y (1). Poverty is a major contributor to these problems, with per capita GNP averaging US$240 (1,3).
High rates of nutritional stunting of young Bangladeshi children can be attributed to both intrauterine growth retardation and postnatal growth faltering (4–6). The latter is caused by limited household food availability and poor infant feeding practices, leading to inadequate energy and nutrient intakes and high rates of infection. Alleviation of low birth weight will require improvements in women’s nutrition and health, and one or more generations to overcome the intergenerational sequelae of maternal malnutrition. On the other hand, mitigation of postnatal growth faltering and specific micronutrient deficiencies should be possible through improved complementary feeding practices and reduced morbidity.
Technical guidelines on optimal complementary feeding practices have been published (7,8). Critical components include: 1) introduction of foods other than breast milk at 6 mo of age, 2) adequate energy density and frequency of feeding of complementary foods, and 3) satisfactory nutrient density of these foods. Before implementing these guidelines, it is essential to understand current child feeding practices, the factors that influence these practices, and possible constraints to improving them. We therefore completed a series of studies using quantitative and qualitative techniques to evaluate complementary feeding practices among rural Bangladeshi infants and identify ways to improve these practices. The studies included: 1) assessment of current dietary intakes, using direct observation of food preparation and consumption in the home, and 2) evaluation of the feasibility and acceptability of increasing the amount of food offered at each meal, increasing meal frequency, enhancing energy density using different recipes, and adding micronutrient supplements to existing foods at the time of preparation or serving, or providing liquid supplements directly to infants. The latter set of studies employed "behavior change trials" and is published elsewhere (9).
In this paper, we report the dietary intake results. Our objectives were as follows: 1) to evaluate the adequacy of energy intake, using various approaches to estimating requirements, 2) to examine the association of energy intake with meal frequency, quantities served and consumed per meal, and energy density of complementary foods, 3) to assess the adequacy of micronutrient intake, and 4) to examine the relation between intake of complementary foods and intake of breast milk, to assess nutritional trade-offs due to possible displacement of breast milk by complementary foods.
|
SUBJECTS AND METHODS |
|---|
|
TOPABSTRACTSUBJECTS AND METHODSRESULTSDISCUSSIONLITERATURE CITED |
|---|
Village selection criteria, infant eligibility, and socioeconomic information.
Observations were completed in villages located within an hour’s travel on a nonmotorized boat from ICDDR,B Matlab Center. The Matlab Health and Demographic Surveillance System supplied information on the number of infants per village and which households included infants of the appropriate age (10). In these villages, most infants in the 6- to 12-mo age range participated in the study, unless their parents refused (n = 2) or the infant was ill and the observations could not be rescheduled (n = 2). Our sample size goal was 
100 infants because that number would permit us to characterize mean intakes of energy, protein, and vitamin A with 8, 10 and 13% precision, respectively, based on the variability in intake observed in previous studies in Bangladesh (11). In total, 135 infants were included in the study. Information on quality of housing and parental education was obtained by observation and parental interview.
Dietary intake.
Trained observers completed one 12-h dietary record for each infant. The assistant remained in the child’s home for 12 h, from 0600 until 1800 h. Maternal recall of foods consumed during the previous 12 h (1800 to 0600 h) was used to estimate total 24-h intake of complementary foods. For the nighttime data, mothers were asked to demonstrate the amounts of food they fed their infants, which the field assistants converted to gram quantities. These nighttime recalls did not include water consumption or snacks, defined as a feeding episode in which <10 g was consumed. Nighttime snacks were excluded because both the field assistants and the mothers found it difficult to estimate such small quantities, people other than the mother often gave snacks, and the total quantities were expected to be extremely small. This final point was verified by the daytime weighed intake data, which demonstrated that when the total amounts of all daytime snacks (all feedings <10 g) were summed, the mean (±SD) daily total was only 6.5 ± 5.0 g/d.
Breast milk nutrient intake determinations. Breast milk intake was determined by weighing the child before and after breast-feeds, as described previously (12), using electronic balances (Medela) with 2-g precision. Insensible water losses were measured twice daily (morning and afternoon) and averaged to correct the test-weighing values (12). For these latter measurements, the mean duration of each observation was 34 ± 10 min, the mean weight lost during the observation period was 14 ± 9 g, and the mean insensible loss correction was 0.059 ± 0.028 g/(kg body weight · min). Breast milk intake for each child was corrected by an amount equal to the product of the child’s own correction factor, total nursing duration, and body weight. The resulting child-specific underestimate of milk intake due to insensible losses (mean ± SD = 26 ± 16 g/12 h) was added to each child’s 12-h breast milk intake (mean 379 ± 117 g/12 h). This sum (mean 405 ± 122 g) was then converted to volume by dividing by the density of breast milk, which was previously measured to be 1037 g/L (12). Breast milk intake over 24 h was extrapolated by dividing by 0.53, the proportion represented by daytime intake, as determined previously (12).
Assumed values were used for breast milk composition. Breast milk fat (25.1 g/L), protein (9.4 g/L), and energy (2470 kJ/L or 0.59 kcal/mL) concentrations were adopted from Brown et al. (13), who examined the lactation performance of undernourished women from a semiurban community of Dhaka. Breast milk micronutrient concentrations were taken from WHO/NUT/98.1 (7), except for vitamin A [226 µg retinol equivalents (RE)/L], which was based on data from Matlab, Bangladesh (14). Possible differences between the actual nutrient concentrations of breast milk and the imputed values are considered in the Discussion.
Measurement of complementary food intake. Using a scale accurate to 2 g, field assistants weighed all foods before and after serving the child. For mixed recipes, all foods included in the recipe were weighed before being added to the preparation, and the final weight of the prepared recipe was determined. The amount that the child consumed was recorded as a proportion of the total recipe, so that the intakes of each food ingredient could be calculated. During analysis of dietary data, a meal was considered to have taken place whenever a new food (or combination of foods) was offered to the infant. It was very rare for more than 1 food or food combination to be served at the same time, i.e., within a 10-min period (this occurred for only 12 of the 636 feeding episodes observed).
The nutrient content of individual foods and recipes was estimated using the software package, The Food Processor (version 7.01), which incorporated USDA food composition data. Data from local food composition tables were added to the database as necessary. The mean energy density of the complementary food regimen was calculated by dividing the daily energy intake by the quantity consumed, not including noncaloric beverages.
The method of rice preparation commonly used in Bangladesh entails adding water to rice and boiling together until the rice is cooked, at which point the excess water is poured off. The discarded broth is commonly used as an animal feed. It is expected that this process increases vitamin and mineral loss, but empirical data are not available. USDA food composition values for parboiled, unenriched rice were used to approximate the nutrient content of rice. Many types of green leafy vegetables are used in Bangladesh. Nutrient values for spinach were used to approximate their nutrient composition. Standardized recipes were created by averaging the food amounts in similar recipes. The nutrient composition of the standardized recipe was used when information on a particular recipe could not be collected because the dish was prepared outside of the study home or before the observation period.
Assessment of adequacy of energy and nutrient intakes. Total nutrient intake from both breast milk and complementary foods was compared with the most recent values for average energy requirements and recommended nutrient intakes (RNIs). Energy requirements were based on energy expenditure and body composition data for breast-fed infants (8,15). RNIs were based on the U.S. Institute of Medicine Dietary Reference Intakes (DRIs) (16–19) or FAO/WHO values (20). Because the DRI and FAO/WHO RNIs differ substantially during infancy for several key nutrients (8), we chose to be conservative in making judgments about the likelihood of deficiency by using the lower value whenever there was a difference between them for a particular nutrient.
Anthropometry. A single field worker was trained to conduct all infant length measurements using standard procedures (21) and a length board accurate to the nearest mm. Weight was measured using balances accurate to 2 g (Medela). When total energy requirements were expressed per unit ideal body weight, ideal weights were calculated using the infant’s actual length and the median weight-for-length from pooled data on breast-fed infants from North America and Europe (22).
Statistical analyses. Statistical analyses were performed using SAS-PC for WINDOWS (version 6.10; SAS Institute). Pearson correlations were used to examine relations among breast-feeding frequency, breast milk intake, meal frequency, and complementary food intake and total energy intake, and multiple linear regression was used when more than one independent variable was included for a given outcome. Means were compared using Student’s t test. Differences were considered significant at P < 0.05. Values in the text are means ± SD.
|
RESULTS |
|---|
|
TOPABSTRACTSUBJECTS AND METHODSRESULTSDISCUSSIONLITERATURE CITED |
|---|
Characteristics of study children. Table 1 presents the mean weight-for-age (WAZ), length-for-age (LAZ), and weight-for-length (WLZ) Z-scores of the study infants. The infants were 6–12 mo of age and mildly wasted and moderately stunted compared with National Center for Health Statistics reference data (23). Z-scores declined as the age of the infants increased.
|
Breast milk consumption. The mean number of breast-feeds during the 12-h weighed intake period was 8.3 ± 2.0 with a mean total duration of 64 ± 22 min. Neither breast-feeding frequency nor total feeding duration changed significantly with age. Both frequency (r = 0.36, P < 0.0001) and total duration (r = 0.18, P < 0.04) of breast-feeds were significantly associated with 12-h breast milk intake.
Mean 12-h breast milk consumption was 0.379 ± 0.123 L at 6–8 mo and 0.400 ± 0.113 L at 9–12 mo. Using the daytime proportion of 0.53, estimated mean 24-h breast milk consumption was 0.715 ± 0.233 L at 6–8 mo and 0.754 ± 0.212 L at 9–12 mo. Assuming an energy density of 2470 kJ/L (0.59 kcal/mL), the mean estimated 24-h energy intake from breast milk was 1766 and 1862 kJ/d (422 and 445 kcal/d) at 6–8 mo and 9–12 mo, respectively (Table 2). Intake did not differ between boys and girls. Controlling for age, infant body weight was significantly associated with breast milk intake (r = 0.21, P < 0.05). Indicators of socioeconomic status (type of housing; parental education) were not associated with breast milk intake.
|
10 g, and "snacks" refer to intakes < 10 g. During the 12-h observation period, 2.7 ± 1.6 feeding episodes and 2.0 ± 1.4 meals were observed. The amount offered per feeding episode ranged from 1 to 374 g (median = 38; 25th–75th percentiles = 10.5–78) and the amount offered per meal ranged from 10 to 374 g (median = 56; 25th–75th percentiles = 32–95.5); the amount consumed at each feeding episode ranged from 1 to 288 g (median = 24; 25th–75th percentiles = 8–55) and the amount consumed at each meal ranged from 10 to 288 g (median = 40; 25th–75th percentiles = 20–67). The percentage of the amount offered that was consumed per feeding ranged from 3 to 100% (mean 76 ± 30%) for feeding episodes and from 11 to 100% (mean 78 ± 25%) for meals. During the 12 h before the observation, 38% of mothers reported feeding their infants meals (10 g); among these women, 1.8 ± 0.8 meals were offered during this period. The mean total number of meals per day was 2.6 ± 1.9 and the total number of feeding episodes, less nighttime snacks, was 3.5 ± 2.0. Meal frequency was higher by 0.2 meals/mo of age (r = 0.20, P = 0.02), although the total amount consumed (g/d) did not differ by age. Table 2 illustrates the amount of food and energy consumed by age group. Foods commonly consumed during the observations included rice, wheat, legumes, vegetables (numerous local varieties of tubers, melons, and greens), fruits (guava, banana, mango, coconut), milk, eggs, and fish. Aside from rice and wheat, the quantities consumed were small. Rice was the major contributor of energy and was included in 53% of meals, either alone (20% of meals), mixed with water, milk, dhal, or vegetable or fish curry (24% of meals), or ground to make "luta," a porridge (9% of meals). Wheat products represented 28% of meals and were usually served as suji (wheat porridge), flat bread, or crackers. Fruit accounted for 11% of meals, and 15% of all meals contained an animal source food, which was usually cow’s milk.
The median energy density of the complementary food regimen was 4.79 kJ/g (1.2 kcal/g); the range was 0.9 to 18.7 kJ/g and the interquartile range was 2.9 kJ/g (0.2–4.5 kcal/g; interquartile range = 0.7 kcal/g) (Table 2). Energy density was inversely correlated with the amount of complementary food consumed (g/d) (r = –0.46, P < 0.0001) and with total daily energy intake from complementary foods (r = –0.32, 0.0002).
Complementary foods supplied 22 and 25% of total energy intake at 6–8 and 9–12 mo, respectively (Table 2). Energy intake (kJ/d) from complementary foods increased only slightly with age (r = 0.15, P = 0.08). Total daily energy intake from complementary foods ranged from 0 to >2092 kJ (500 kcal)/d, with 47% of infants consuming <415 kJ/d (100 kcal/d). Energy intake from complementary foods was positively correlated with the number of feeding episodes per 24 h (r = 0.67, P < 0.0001), the amount (g) consumed per 24 h (r = 0.82, P < 0.0001), and the amount (g) served per meal during the 12-h weighed intake period (r = 0.73, P < 0.0001). Maternal educational level was positively related to energy intake from complementary foods (r = 0.18, P < 0.04).
The theoretical mean amount of energy needed from complementary foods, estimated as the difference between total energy requirements and the mean breast milk energy consumption in the current study, was 808 kJ (193 kcal) at 6–8 mo and 1008 kJ (241 kcal) at 9–12 mo. Energy intake from complementary foods, as a percentage of energy needed from complementary foods, averaged 63% at 6–8 mo and 61% at 9–12 mo (Table 2).
Total energy intake. Total energy intakes by 6–8 mo infants were 88% of estimated absolute energy requirements, 106% of requirements/kg body weight, and 97% of requirements/kg ideal body weight for length. The corresponding percentages for 9–12 mo infants were 86, 105, and 94% for these 3 estimates, respectively.
Total energy intake was positively correlated with energy intake from breast milk (r = 0.69, P < 0.0001), energy intake from complementary food (r = 0.44, P < 0.0001), complementary food meal frequency (r = 0.31, P = 0.0003), and quantity consumed (g) per meal (r = 0.21, P = 0.02), but not with energy density of complementary foods (r = –0.09, P = 0.34), maternal education (r = 0.04, P = 0.65), or type of housing (r = –0.007, P = 0.93). When both meal frequency and quantity per meal were included in the same model, the former was significantly associated with total energy intake (P = 0.005), but the latter was not (P = 0.36).
Nutrient intake. Tables 3, and 4 compare total nutrient intakes with the RNIs at 6–8 and 9–12 mo, respectively, and illustrate the contribution of breast milk and complementary food to total intakes. Breast milk was the major contributor of all nutrients except vitamin B-6 and iron. Protein intake exceeded the recommended amounts in both age groups. Nutrient intakes that fell short of the recommended amounts included vitamin A, folate, pantothenic acid, riboflavin, thiamin, vitamin B-6, vitamin D, calcium, iron, magnesium, phosphorus, potassium and zinc. The mean nutrient density of the complementary food diet was below the desired nutrient density for vitamin A, folate, niacin, riboflavin, thiamin, vitamin B-6, vitamin C, calcium, iron, and zinc (data not shown) (8).
|
|
10 g) was associated with a decrease of 1.0 (r = –0.59, P < 0.0001) and 0.5 (r = –0.39, P < 0.0005) breast-feeds respectively, over the 12-h observation period. Using recall data to approximate 24-h values, each additional meal corresponded to a decrease of 0.9 (r = –0.55, P < 0.0001) and 0.3 (r = –0.22, P < 0.06) breast-feeds for 6–8 mo and 9–12 mo old infants, respectively. Similarly, energy intake from complementary foods was inversely associated with energy intake from breast milk. Over the 12-h observation period, each additional 4.2 kJ (1 kcal) from complementary food was associated with a decrease of 0.9 kJ (0.22 kcal) from breast milk at 6–8 mo (r = –0.29, P < 0.02) and 1.3 kJ (0.30 kcal) (r = –0.42, P < 0.002) at 9–12 mo. Approximating 24-h intake by using recall data for complementary food and estimates of nighttime breast milk consumption, each additional 4.2 kJ (1 kcal) from complementary food was associated with a decrease of 1.7 (0.41 kcal) from breast milk at 6–8 mo (r = –0.32, P < 0.01) and 2.1 kJ (0.51 kcal) (r = –0.42, P < 0.002) at 9–12 mo.
We calculated the theoretical changes in intake of selected nutrients if an infant consumed an additional 418 kJ (100 kcal) of complementary food, leading to a displacement from the diet of 184 kJ (44 kcal) of breast milk, the mean estimated displacement for infants in both age groups (Table 5). This increase in complementary food intake would result in a 17% increase in protein intake, but only small increases (<10% of the RNI) in the intakes of iron, zinc, calcium, and riboflavin, and a small decrease in the intakes of vitamins A and C. The estimates for iron, zinc, and calcium do not take into account the potential differences in bioavailability from complementary foods vs. breast milk.
|
|
DISCUSSION |
|---|
|
TOPABSTRACTSUBJECTS AND METHODSRESULTSDISCUSSIONLITERATURE CITED |
|---|
Adequacy of energy intake. There are several possible approaches to assessing the adequacy of infant energy intake. Comparing energy intakes to absolute requirements has the advantage of allowing extra energy per kilogram for catch-up growth of children with low body weight due to previous nutritional growth retardation. Low body weight may be due to intrauterine growth retardation, postnatal nutritional deficiencies, and/or repeated illnesses. Normal birth weight infants are usually born with adequate reserves of nutrients, such as iron and zinc, for the first 6 mo of life, but infants born with low birth weight may exhaust those stores and begin experiencing growth retardation very early in life (7). Although a portion of intrauterine, infantile, and multigenerational growth stunting can be overcome (33), absolute energy requirements probably overestimate the true needs of this population because even with optimal postnatal nutrition and care, it is unlikely that these infants will achieve their full genetic potential in height.
Using requirements based on energy per kilogram body weight has the advantage of accounting for the small size of these infants, but does not provide energy for catch-up growth nor does it account for low body weight due to wasting. Accordingly, because the infants in this study were both stunted and thin, requirements based on energy per kilogram body weight probably underestimate desirable energy intake.
A third approach, using energy requirements based on ideal body weight for length, accounts for wasting by substituting expected weight for length based on values from a well-nourished population, but does not provide for catch-up from stunting. These values may result in an overestimate of requirements if Bangladeshi infants are genetically destined to be thinner than children in the reference population. Anthropometric data from a 7-country study of breast-fed infants of well-educated mothers indicate that Indian infants are significantly lower in weight for length than infants from other regions of the world (34). On the other hand, basing energy needs on ideal weight for length may underestimate requirements by not allowing sufficient extra energy for catch-up growth in length. Of the 3 approaches, the 3rd one probably provides the best estimate of the children’s true energy needs.
In these infants, total energy intake was low compared with absolute energy requirements, whereas intake per kilogram was at or above requirements. Using the 3rd approach, based on energy needs per kilogram ideal weight for length, intakes were 94–97% of requirements. There are several potential errors when estimating energy intakes of breast-fed infants. For example, we assumed a breast milk energy density of 2470 kJ/L (0.59 kcal/mL), based on the value reported by Brown et al. (24) for Bangladeshi women with a mean BMI of 17.8 kg/m2. However, if the women in the current study had a higher BMI than in the study by Brown et al., we may have underestimated the energy density of breast milk because it is correlated with maternal fatness (13). Rice et al. (14) recently reported a BMI of 18.9 from women in the Matlab area. Other possible sources of error include the assumptions about the amount of breast milk consumed at night, the inability to collect information on snacks of complementary foods consumed at night (although these amounts were likely to be quite small), and the estimate of the energy density of rice.
The low WLZ of infants in this study (mean, –0.9) suggests inadequate energy intake. The mean WLZ of Indian infants of well-educated mothers at this age was similar (approximately –0.7) (34), making it unclear how to interpret this finding. Frequent illness is a likely contributor to the low mean WLZ. However, morbidity data were not collected and dietary data were not collected on days when infants were overtly ill; thus, it is not possible to estimate the effect of morbidity in the present study.
Mean meal frequency and energy density were generally consistent with recommendations. However, the relatively high energy density observed may reflect foods and preparation techniques that do not result in the consistency needed to facilitate infant feeding. This may have constrained the amount of complementary foods consumed per meal, which was low. This is supported by the observation that energy intake from complementary foods was positively correlated with meal frequency and quantities offered and consumed, but negatively correlated with the energy density of the diet. Despite the fact that the amount of energy from complementary foods offered to the infants was only 74% of the recommended amounts, only 72% of the amount of food offered was consumed. Thus, the infants were apparently unwilling or unable to consume the amounts offered. There are several possible explanations. First, the small size of the infants and limited potential for catch-up growth may explain their low energy intakes. Second, the caregivers may have offered inappropriate foods (e.g., improper consistency) or used feeding methods that made it difficult for the infants to consume adequate amounts. Third, the infants’ appetites may have been depressed due to chronic subclinical infections or micronutrient deficiencies.
Adequacy of micronutrient intake. For several micronutrients, the mean total intake (from both breast milk and complementary food) was far below the RNI. Conclusions about the adequacy of micronutrient intakes depend on assumptions made about breast milk composition and infant nutrient requirements. Breast milk micronutrient values potentially affected by maternal status include vitamin A, riboflavin, thiamin, vitamin B-6, vitamin B-12, and selenium (value ranges are presented in Table 3 footnotes). Those that are not likely to be affected by maternal status include folic acid, vitamin D, calcium, iron, copper, and zinc (7). In this study, mean intakes of protein, niacin, folate (at 9–12 mo), vitamin B-12, vitamin C, selenium, and copper equaled or exceeded the RNI, regardless of the assumptions regarding breast milk nutrient concentration. By contrast, mean intakes of folate (at 6–8 mo), pantothenic acid, riboflavin, thiamin, vitamin B-6, vitamin D, calcium, iron, magnesium, phosphorus, potassium, and zinc intakes were less than the RNI, regardless of the assumptions employed. Mean intakes were particularly low for iron (8–9% of the RNI), vitamin D (12–13% of the RNI), zinc (40–45% of the RNI), and vitamin B-6 (50% of the RNI), although it should be noted that vitamin D requirements can be met by adequate exposure to sunlight (35). The adequacy of vitamin A intake depends on which assumptions are used for breast milk concentrations. Using an estimate of 226 µg/L (14), mean vitamin A intakes were only 44–48% of the RNI.
The nutrient recommendations used in this study were based on recently published DRIs (16–19) or RNIs (20). The proportion of a group that is at risk of nutrient inadequacy can be estimated by using the Estimated Average Requirement (EAR) Cut Point Method (36). This is not yet possible for infants because EARs for infants are presently available only for iron and zinc. All other vitamin and mineral intake recommendations are Adequate Intakes (AI), which during infancy are based on observed intakes of infants in the United States (8,15). By definition, the AI should be greater than the EAR and possibly the RDA. Thus, the proportion of a population with intakes below the AI is likely to be an overestimate of the prevalence of nutrient inadequacy. For this reason, there is uncertainty about the percentage of infants with inadequate micronutrient intakes in our study population.
Programmatic implications. Assuming that total energy intake is indeed lower than desirable, one possible recommendation would be to increase the amount of complementary food offered without decreasing meal frequency or energy density. However, this might not be successful considering that not all of the food currently offered was consumed. Moreover, increased intake of complementary foods is associated with some decrease in intake of breast milk, although the net effect on total energy intake is positive. The magnitude of the inverse relation between breast milk and complementary food intake observed in this study is in agreement with values reported by Drewett et al. (37) from an observational study in Thailand [a displacement of 1.3–1.7 kJ (0.3–0.4 kcal) of breast milk for each additional 4.18 kJ (1 kcal] from complementary food among similarly aged infants). Even if the Bangladeshi infants consumed more energy, however, the effect on total micronutrient intakes might be negligible due to poor nutrient density of the complementary foods, or there might even be adverse effects because of poor microbiological quality and displacement of breast milk. Our estimates indicate that an increase in energy intake from the currently consumed complementary foods would not substantially improve micronutrient intake (Table 5).
Increasing the variety and amount of the foods consumed could reduce deficits in vitamin A, folate, pantothenic acid, thiamin, riboflavin, vitamin B-6, magnesium, phosphorus, and potassium. However, major changes in the diet, probably necessitating a large increase in the consumption of animal source foods, would be required to achieve adequate intakes of iron and zinc. Fortification or supplementation may be the most efficient way to achieve adequate intakes of these nutrients. Recommendations have to focus concomitantly on increasing the nutrient density of the diet, improving palatability of foods, and educating caregivers on appropriate feeding practices. In addition, the microbiological safety of complementary foods should be emphasized. Because microbiologically contaminated complementary foods are a common cause of diarrhea, recommendations to increase the quantity, frequency, or variety of foods offered should be accompanied by appropriate food safety guidelines.
|
ACKNOWLEDGMENTS |
|---|
|
FOOTNOTES |
|---|
3 Abbreviations used: AI, Adequate Intakes; DRI, Dietary Reference Intakes; EAR, Estimated Average Requirement; GNP, Gross National Product; ICDDR,B, Centre for Health and Population Research; LAZ, length-for-age Z-score; RE, retinol equivalent; RNI, recommended nutrient intake; WAZ, weight-for-age Z-score; WLZ, weight-for-length Z-score.
Manuscript received 14 April 2004. Initial review completed 10 June 2004. Revision accepted 8 November 2004.
|
LITERATURE CITED |
|---|
|
TOPABSTRACTSUBJECTS AND METHODSRESULTSDISCUSSIONLITERATURE CITED |
|---|
1. UNICEF (1998) State of the World’s Children 1998 United Nations New York, NY.
2. Food and Agriculture Organization (1999) Nutrition Country Profile Bangladesh 1999 FAO Rome, Italy .
3. Nutritional Surveillance Project (1999) 1998 NSP Annual Report: National and Divisional Trends Among Children and Households in Rural Bangladesh 1999 Helen Keller International/Institute of Public Health Nutrition Dhaka, Bangladesh .
4. Arifeen, S. E., Black, R. E., Caulfield, L. E., Antelman, G., Baqui, A. H., Nahar, Q., Alamgir, S. & Mahmud, H. (2000) Infant growth patterns in the slums of Dhaka in relation to birth weight, intrauterine growth retardation, and prematurity. Am. J. Clin. Nutr. 72:1010-1017.
5. ACC/SCN (1999) Nutrition Policy Paper #18. Low Birthweight Conference June 14–17, 2000, Dhaka, Bangladesh 1999.
6. Brown, K. H., Black, R. E., Becker, S. & Hoque, A. (1982) Patterns of physical growth in a longitudinal study of young children in rural Bangladesh. Am. J. Clin. Nutr. 36:294-302.
7. Brown, K., Dewey, K. & Allen, L. (1998) Complementary Feeding of Young Children in Developing Countries: A Review of Current Scientific Knowledge 1998 WHO Geneva, Switzerland .
8. Dewey, K. G. & Brown, K. H. (2003) Update on technical issues concerning complementary feeding of young children in developing countries and implications for intervention programs. Food Nutr. Bull. 24:5-28.[Medline]
9. Kimmons, J. E., Dewey, K. G., Haque, E., Chakraborty, J.M.S., Osendarp, S.J.M. & Brown, K. H. (2004) Behavior change trials to assess the feasibility of improving complementary feeding practices and micronutrient intake of infants in rural Bangladesh. Food Nutr. Bull. 25:228-238.[Medline]
10. Anonymous (1998) Health and Demographic Surveillance System 1998 International Center for Diarrhoeal Disease Research Dhaka, Bangladesh .
11. Brown, K. H., Black, R. E., Becker, S., Abdul Alim, A.R.M. & Merson, M. H. (1982) Consumption of foods and nutrients by weanlings in rural Bangladesh. Am. J. Clin. Nutr. 36:878-889.
12. Brown, K. H., Black, R. E., Robertson, A. D., Akhtar, N. A., Ahmed, M. G. & Becker, S. (1982) Clinical and field studies of human lactation: methodological considerations. Am. J. Clin. Nutr. 35:745-756.
13. Brown, K. H., Akhtar, N. A., Robertson, A. D. & Ahmed, M. G. (1986) Lactational capacity of marginally nourished mothers: relationships between maternal nutritional status and quantity and proximate composition of milk. Pediatrics 78:909-919.
14. Rice, A. L., Stoltzfus, R. J., de Francisco, A., Chakraborty, J., Kjolhede, C. L. & Wahed, M. A. (1999) Maternal vitamin A or ß-carotene supplementation in lactating Bangladeshi women benefits mothers and infants but does not prevent subclinical deficiency. J. Nutr. 129:356-365.
15. Butte, N. F., Wong, W. W., Hopkinson, J. M., Heinz, C. J., Mehta, N. R. & Smith, E. O. (2000) Energy requirements derived from total energy expenditure and energy deposition during the first 2 y of life. Am. J. Clin. Nutr. 72:1558-1569.
16. Institute of Medicine (U.S.) (2000) Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids 2000 National Academy Press Washington, DC.
17. Institute of Medicine (U.S.) (2001) DRI, Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc 2001 National Academy Press Washington, DC.
18. Institute of Medicine (U.S.) (1997) DRI, Dietary Reference Intakes: for Calcium, Phosphorus, Magnesium, Vitamin D, and Fluoride 1997 National Academy Press Washington, DC.
19. Institute of Medicine (U.S.) (1998) Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B-6, Folate, Vitamin B-12, Pantothenic Acid, Biotin, and Choline 1998 National Academy Press Washington, DC.
20. FAO/WHO Expert Consultation (2002) Vitamin and Mineral Requirements in Human Nutrition 2002 WHO Geneva, Switzerland.
21. Gibson, R. S. (1990) Principles of Nutritional Assessment 1990 Oxford University Press New York, NY.
22. Dewey, K. G., Peerson, J. M., Brown, K. H., Krebs, N. F., Michaelsen, K. F., Persson, L. A., Salmenpera, L., Whitehead, R. G. & Yeung, D. L. (1995) Growth of breast-fed infants deviates from current reference data: a pooled analysis of US, Canadian, and European data sets. World Health Organization Working Group on Infant Growth. Pediatrics 96:495-503.[Medline]
23. Hamill, P.V.V., Drizd, T. A., Johnson, C. L., Reed, R. B. & Roche, A. F. (1977) NCHS growth curves for children: birth-18 years. United States 1977 Vital and Health Statistics Series 11, No. 165 Hyattsville, MD.
24. Brown, K. H., Robertson, A. D. & Akhtar, N. A. (1986) Lactational capacity of marginally nourished mothers: infants’ milk nutrient consumption and patterns of growth. Pediatrics 78:920-927.
25. Underwood, B. A. (1994) Maternal vitamin A status and its importance in infancy and early childhood. Am. J. Clin. Nutr. 59:517S-524S.
26. Horwitt, M. K., Harper, A. E. & Henderson, L. M. (1981) Niacin-tryptophan relationships for evaluating niacin equivalents. Am. J. Clin. Nutr. 34:423-427.
27. Deodhar, A. O., Rajalakshmi, R. & Ramakrishnan, C. V. (1964) Studies on human lactation. Part III. Effect of dietary vitamin contents of breast milk. Acta Paediatr. 53:42-48.
28. Bates, C. J., Prentice, A. M., Paul, A. A., Prentice, A., Sutcliffe, B. A. & Whitehead, R. G. (1982) Riboflavin status in infants born in rural Gambia, and the effect of a weaning food supplement. Trans. R. Soc. Trop. Med. Hyg. 76:253-258.[Medline]
29. Prentice, A. M., Lunn, P. G., Watkinson, M. & Whitehead, R. G. (1983) Dietary supplementation of lactating Gambian women. II. Effect on maternal health, nutritional status and biochemistry. Hum. Nutr. Clin. Nutr. 37:65-74.[Medline]
30. Institute of Medicine (U.S.) (1991) Nutrition during Lactation 1991 National Academy Press Washington, DC.
31. Levander, O. A., Moser, P. B. & Morris, V. C. (1987) Dietary selenium intake and selenium concentrations of plasma, erythrocytes, and breast milk in pregnant and postpartum lactating and nonlactating women. Am. J. Clin. Nutr. 46:694-698.
32. Gibson, R. S., Ferguson, E. L. & Lehrfeld, J. (1998) Complementary foods for infant feeding in developing countries: their nutrient adequacy and improvement. Eur. J. Clin. Nutr. 52:764-770.[Medline]
33. Martorell, R., Ramakrishnan, U., Schroeder, D. G., Melgar, P. & Neufeld, L. (1998) Intrauterine growth retardation, body size, body composition and physical performance in adolescence. Eur. J. Clin. Nutr. 52:S43-S53.
34. WHO Working Group on the Growth Reference Protocol & WHO Task Force on Methods for the Natural Regulation of Fertility (2000) Growth patterns of breastfed infants in seven countries. Acta Paediatr. 89:215-222.[Medline]
35. Committee on Nutrition & Kleinman, R. E. (1998) Pediatric Nutrition Handbook 4th ed. 1998 American Academy of Pediatrics Elk Grove Village, IL.
36. Institute of Medicine (U.S.) (2000) Dietary reference Intakes: a Report of the Subcommittees on Interpretation and Uses of Dietary Reference Intakes and the Standing Committee on the Scientific Evaluation of Dietary Reference Intakes 2000 National Academy Press Washington, DC.
37. Drewett, R., Amatayakul, K., Wongsawasdii, L., Mangklabruks, A., Ruckpaopunt, S., Ruangyuttikarn, C., Baum, D., Imong, S., Jackson, D. & Woolridge, M. (1993) Nursing frequency and the energy intake from breast milk and supplementary food in a rural Thai population: a longitudinal study. Eur. J. Clin. Nutr. 47:880-891.[Medline]
This article has been cited by other articles:
|
|
 |
|
  K. M. Lunney, A. L. Jenkins, N. V. Tavengwa, F. Majo, D. Chidhanguro, P. Iliff, G. T. Strickland, E. Piwoz, L. Iannotti, and J. H. Humphrey HIV-Positive Poor Women May Stop Breast-feeding Early to Protect Their Infants from HIV Infection although Available Replacement Diets Are Grossly Inadequate J. Nutr., February 1, 2008; 138(2): 351 - 357. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M M. Islam, J. M Peerson, T. Ahmed, K. G Dewey, and K. H Brown Effects of varied energy density of complementary foods on breast-milk intakes and total energy consumption by healthy, breastfed Bangladeshi children. Am. J. Clinical Nutrition, April 1, 2006; 83(4): 851 - 858. [Abstract] [Full Text] [PDF]
|
|
| |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
