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Figure 1. Histological appearance of kidneys from female Sprague-Dawley rats fed diets differing in Ca and P concentrations for 16 wk (see text for details). Section from outer capsule (at left) to inner stripe of outer medulla (at right); von Kossa stain; original X75. Ca deposits appear as large black granules against a lighter background. (A) Diet AIN93, 5 g Ca + 3 g P/kg diet, Ca: P molar ratio 1.07 by analysis. (B) Diet 4.0x, 20 g Ca + 12 g P/kg diet, Ca: P molar ratio 1.17 by analysis. (C) Diet AIN76, 5 g Ca + 5 g P/kg diet, Ca: P molar ratio 0.66 by analysis.

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