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Absorption of Vitamin E by the Rat from a Low Fat Diet

Health and Nutrition Research Division, Tennessee Eastman Company, Rochester, New York 14603

To determine whether absorption and utilization of vitamin E are as efficient on a low fat diet as on a diet containing abundant quantities of fat, groups of rats were fed for 8 weeks with low or high fat diets supplemented with graded levels of d-a-tocopheryl acetate (0 to 7.61 IU/100 g diet). Erythrocytes from animals fed the low fat diets were less susceptible to hemolysis by dialuric acid than those from animals fed the high fat diets. Hepatic storage of the supplemented vitamin E was not influenced by dietary fat except at the highest dose administered, at which level the high fat diet enhanced storage. Thus, by both criteria, vitamin E is effectively absorbed and utilized whether the animal is fed a low or a high fat diet.