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Retention of Radiocesium by Rats Before and After Weaning¹

Department of Physical Biology, New York State Veterinary College, Cornell University, Ithaca, New York 14850

Rat pups were given intraperitoneal injections of ¹³⁴Cs at 4 days of age, and the retention of the radiocesium was followed by whole-body counting. Up to the time of weaning, the pups lost half of the radiocesium every 10.9 days. After weaning, the rate of loss increased markedly and the body retention function became multiexponential rather than the single exponential observed during nursing. Experimental procedures ruled out recycling of radiocesium through the dams and the physical nature of the diet after weaning as being contributory factors to the changes observed in cesium retention. The experiments suggest that the higher potassium intake after weaning may be responsible for the sharp change in retention.

Manuscript received 15 July 1969.