QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Purchase Article View Shopping Cart Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Ginsburg, J. M. Articles by Heggeness, F. W. Search for Related Content PubMed PubMed Citation Articles by Ginsburg, J. M. Articles by Heggeness, F. W.

Adaptation in Monosaccharide Absorption in Infant and Adult Rats¹

Department of Physiology, University of Rochester School of Medicine and Dentistry, Rochester, New York

The influence of carbohydrate intake on the ontogeny of intestinal monosaccharide transport in the rat was examined. Nutritionally adequate, carbohydrate-free or 60% glucose diets were provided to litters of rats starting 10 days following parturition. Absorptive rates for glucose were determined in the young animals and adults (mothers) following stomach loading after 8 to 18 weeks. Intestinal transport rates for monosaccharides were sensitive to the presence of dietary carbohydrate. Rate of glucose and galactose absorption in all animals fed the carbohydrate-free diets was 75% of that in animals fed high glucose intakes. Similar differences in absorptive rates in young animals were also present in isolated intestinal loops in situ. In young animals glucose absorptive rates increased to greater than control levels promptly, following addition of glucose to the carbohydrate-free diet.

² Present address: Department of Physiology, Medical College of Georgia, Augusta, Georgia 30902.

³ Supported in part by Career Development Award no. 5 KO3 HD14904-07.

Manuscript received 29 May 1968.