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Journal of Nutrition Vol. 96 No. 1 September 1968, pp. 157-162
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Deposition of Linoleic and Linolenic Acid in Rat Adipose Tissue1

Jeannette H. Forsyth2, Roberta Shaftel and D. M. Hegsted

Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts

Studies were designed to determine whether there was competition between linoleic and linolenic acid deposition in adipose tissue of rats. Diets containing different amounts and ratios of linoleic and linolenic acid were fed to adult rats. The deposition of these and other fatty acids into the epididymal fat pad was measured by comparing the fatty acid content of the left pad at the beginning and the right pad at the termination of the experiment. The deposition of these fatty acids appeared to be linearly related to the amount eaten, when the total fat content of the diet and the time of the experiment. The deposition of these fatty acids appeared to be linearly related to the amount eaten, when the total fat content of the diet and the time of the experiment were the same, and no interrelation or competition between these fatty acids in the formation of adipose tissue could be shown.


1 Supported in part by Public Health Service Research Grants nos. AM-06245 and 5-K6-AM-18,455 from the National Institute of Arthritis and Metabolic Diseases, and the Fund for Research and Teaching, Department of Nutrition, Harvard School of Public Health.

2 Present address: Assistant Professor of Biology, Simmons College, Boston, Massachusetts.

Manuscript received 30 March 1968.





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