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Effect of Imbalanced Diets Containing Natural Proteins on Appetite and Body Composition in the Rat^{1, 2,}

Department of Food Sciences and Experimental Nutrition, School of Pharmacy and Biochemistry, University of Buenos Aires, Argentina

Experiments were undertaken to determine some biochemical changes that occur in protein-depleted rats fed imbalanced diets for 24 hours. The diets used contained only natural proteins—wheat gluten and defatted whole egg—mixed in different amounts. Basal diets contained only defatted whole egg having the same level of "complete protein" as the corresponding imbalanced ones. Animals fed imbalanced diets showed a typical consumption curve, but their total intake was lower than that of the control animals. After a subsequent 4-hour fast, the imbalanced rats lost a significantly higher percentage of weight than the corresponding groups fed the balanced diet. Body water content was increased in imbalanced rats, but that value returned to a more normal figure after fasting subsequent to the feeding period. Hematocrit value was also higher in rats fed the imbalanced diets than in control animals, but the values tended to be closer after the fasting period.

² This paper is part of a thesis to be presented in partial fulfillment of the requirement for the Doctor's degree, of the University of Buenos Aires, Buenos Aires, Argentina.

Manuscript received 27 November 1967.