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Copper, Manganese, Cobalt, and Molybdenum Balance in Pre-adolescent Girls1,2,

R. W. Engel, N. O. Price and R. F. Miller3

Department of Biochemistry and Nutrition, Research Division, Virginia Polytechnic Institute, Blacksburg, Virginia

Metabolic balance data were obtained on 36 pre-adolescent girls, aged 6 to 10 years, consuming measured intakes of diets varying in protein from predominantly animal to all-plant protein and varying in protein content so that intake per child ranged from 0.6 to 3.0 g/kg body weight. From food, fecal and urine analyses, estimates of daily dietary requirements for equilibrium for Cu, Mn, and Co were found to be 1.3 mg, 1.0 mg, and 7.7 µg, respectively. Suggested daily allowances for these elements are 2.5 mg, 1.25 mg, and 15 µg, respectively, based on estimates of growth needs, integumental losses, and reasonable margins of safety. Mo was found to be retained by all subjects when intakes approached 100 µg/child/day.

1 Publication no. 23 in the Series Metabolic Patterns in Pre-adolescent Children. This study was a phase of the Southern Regional Research Project S-28, Requirements and Utilization of Selected Nutrients by Pre-adolescent Children, supported in part by funds appropriated to the U.S. Department of Agriculture under the Research and Marketing Act of 1946 and the Hatch Act, as amended. The Human Nutrition Research Division of the Agricultural Research Service was a cooperator in this project.

2 This study was supported, in part, by the Nutrition Foundation, Inc., New York.

3 Deceased.

Manuscript received 10 February 1967.


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 Hum Exp ToxicolHome page
G. Naylor and J. Harrison
Gastrointestinal iron and cobalt absorption and iron status in young rats and guinea pigs
Human and Experimental Toxicology, December 1, 1995; 14(12): 949 - 954.
[Abstract] [PDF]


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