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Research Division, Wyeth Laboratories, Radnor, Pennsylvania
In view of the criticisms of the compositions of the salt mixtures commonly used in rat diets, growth studies were carried out with a mineral mixture based on the requirements listed by the National Research Council (NRC). Addition of sulfate to this mixture improved growth and the protein efficiency ratio. All mineral requirements estimated by the NRC were adequate for maximal growth of male weanling rats. A close correlation was noted between estimated mineral requirements and amounts present in fat-free tissues of adult rats.
Manuscript received 15 March 1966.