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Journal of Nutrition Vol. 88 No. 3 March 1966, pp. 345-350
Copyright © 1966 by American Society for Nutrition
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Influence of Vitamin D on Linear Growth of Normal Full-term Infants1

Samuel J. Fomon, M. Kabir Younoszai and Lora N. Thomas

Department of Pediatrics, State University of Iowa, Iowa City, Iowa

Because of the possibility that moderate overdosage of vitamin D may interfere with linear growth of human infants, rates of growth and serum concentrations of calcium and inorganic phosphorus were studied in normal full-term male infants fed ad libitum with evaporated milk formulas that supplied either 350 to 550 USP units of vitamin D or 1,380 to 2,170 USP units daily. A group of breastfed male infants receiving 300 USP units of vitamin D daily was also studied. Rates of growth in length and weight and serum concentrations of calcium were similar in the 3 groups. Serum concentrations of inorganic phosphorus were similar in the 2 groups fed evaporated milk; concentrations in these groups were significantly greater than those of the breastfed infants. The study fails to provide evidence that moderate overdosage of vitamin D interferes with rate of growth of normal infants.

1 Supported in part by Public Health Service Research grants no. HD-00383, 5 K3 HD-2465, and 5 T1 AM 5246, and in part by a grant from the Evaporated Milk Association.

Manuscript received 5 November 1965.




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