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Journal of Nutrition Vol. 87 No. 2 October 1965, pp. 211-216
Copyright © 1965 by American Society for Nutrition
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Utilization of Calcium and Sodium Sulfate by the Rat1, 2,

Grace M. Button3, R. Glenn Brown3,4, Frances G. Michels5 and John T. Smith

Department of Nutrition, University of Tennessee, Knoxville, Tennessee

In order that calcium sulfate might be established as a satisfactory source of inorganic sulfur to use in altering the ratio of neutral to inorganic sulfur in purified diets, salt mixtures incorporating calcium sulfate and sodium sulfate at levels sufficient to give 0.10 and 0.42% of inorganic sulfur in the diet were compared with each other and with the Hubbell-Mendel-Wakeman salt mixture. The comparative effect of these salts on growth, feed efficiency, absorption, fecal and urinary excretion, blood level and the incorporation of sulfate into cartilage mucopolysaccharides was studied. Calcium sulfate appeared to function as well as, if not better than, sodium sulfate; no ill-effects of either salt were observed. When the animals received 0.10% and 0.42% of sulfate a small increase in feed efficiency was obtained over that recorded with 0.02% of sulfate as furnished by the level of Hubbell-Mendel-Wakeman salt mixture used in this investigation.

1 Presented in part at the Annual Meeting of the Federation of American Societies for Experimental Biology in Chicago, 1964. Button, G. M., R. G. Brown, F. G. Michels and J. T. Smith 1964 The influence of inorganic sulfate on the neutral sulfur requirement of the rat. Federation Proc., 23: 184 (abstract).

2 Published by permission of the Director, Tennessee Agricultural Experiment Station.

3 Holder of a National Defense Education Act predoctoral fellowship during a part of this study.

4 Present address: Department of Food and Nutrition, Drexel Institute of Technology, Philadelphia.

5 Holder of a General Foods Fellowship during this study.

Manuscript received 9 June 1965.




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