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Journal of Nutrition Vol. 84 No. 1 September 1964, pp. 71-76
Copyright © 1964 by American Society for Nutrition
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Studies in Infantile Malnutrition

III. Effect of Protein and Calorie Intake on Nitrogen Retention1

George G. Graham, Angel Cordano and Juan M. Baertl

British American Hospital, Lima, Peru

In severe marasmus and in partially recovered malnourished infants, the retention of nitrogen is shown to depend on the total intake of calories as well as on the quantity and quality of protein ingested. If the caloric requirements are not met, protein is "wasted." Early in the treatment of patients with hypoalbuminemia, with or without other signs of kwashiorkor, nitrogen retention is, to a great extent, independent of caloric intake but closely related to the quantity and quality of protein in the diet. After this initial period of repletion, nitrogen retention is also dependent on caloric intake.

1 This investigation was supported by Public Health Service Research Grants AM-4635 and AM-5935 from the National Institutes of Health.

Manuscript received 21 January 1964.




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