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Plasma and Liver Lipids of Mice as Influenced by Dietary Protein and Sulfur-containing Amino Acids¹

U. S. Army Medical Research and Nutrition Laboratory, Fitzsimons General Hospital, Denver, Colorado

The influence of dietary protein level and of sulfur-containing amino acids on plasma and liver lipids was studied in young adult mice. Increasing the level of dietary protein resulted in decreased plasma and liver cholesterol and liver fat levels. A greater hypocholesterolemic effect of dietary protein was observed in mice fed a cholesterol-supplemented diet. The increased level of sulfur-containing amino acids could, in part, account for the hypocholesterolemic effect of dietary protein.

Manuscript received 24 April 1964.

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