Journal of Nutrition

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Journal of Nutrition Vol. 83 No. 2 June 1964, pp. 103-106
Copyright © 1964 by American Society for Nutrition
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Glycerol Metabolism in Choline-deficient Rats1

William J. Longmore and A. Baird Hastings

Scripps Clinic and Research Foundation, La Jolla, California

The metabolism of glycerol-1,3-C14 by liver slices of choline-deficient and normal liver was compared. The uptake of glycerol and its conversion to glycogen was markedly decreased in the choline-deficient liver, whereas glycerol conversion to glucose and CO2 was normal. The incorporation of glycerol into the glycerol moiety of liver phospholipids decreased in the choline-deficient tissue, whereas incorporation of inorganic P32 into the phospholipid remained normal or increased.

1 This work was supported in part by a grant-in-aid from the U. S. Public Health Service, Grant no. AM-03404, National Institute for Arthritis and Metabolic Diseases.

Manuscript received 31 January 1964.




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