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A New Toxicant Occurring Naturally in Certain Samples of Plant Foodstuffs^1,2,

I. Results Obtained in Preliminary Feeding Trials

Eight Figures

Department of Experiment Station Chemistry, South Dakota State College, Brookings

1. An apparently new nutritional disturbance, associated with plant material from particular localities, is described.

2. The effects are probably produced by a definite toxic compound or compounds.

3. Thirteen samples of various cereal grains, including corn, wheat, barley, and emmer, from the affected areas produced death in 299 out of 325 white rats within 100 days.

4. Definite pathologic effects produced by the toxic materials are described.

² These investigations are being carried out under the Purnell Fund and with the cooperation of the Bureau of Chemistry and Soils, Burean of Plant Industry, Bureau of Animal Industry, and Bureau of Home Economics of the United States Department of Agriculture.

Manuscript received 22 March 1934.