QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Purchase Article View Shopping Cart Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Söderhjelm, L. Search for Related Content PubMed PubMed Citation Articles by Söderhjelm, L.

Influence of Pyridoxine and Dietary Fat on the Distribution of Serum Fatty Acids in Dogs^1,2,

Bruce Lyon Memorial Research Laboratory of the Children's Hospital of the East Bay, Oakland, California and the Department of Nutritional Sciences, University of California, Berkeley, California

Studies were performed concerning the relative distribution of fatty acids in the blood serum of 6 adult Beagle dogs, two German short-hair puppies and 6 mongrel puppies that received diets deficient in linoleic acid or vitamin B₆ or both. The presence or absence of linoleic acid caused marked changes in the fatty acid spectrum in the serum, whereas the presence or absence of pyridoxine in the diet did not influence the relative content of arachidonic acid in the blood serum. With two rapidly growing young animals (the German short-hair puppies) however, it was noted that arachidonic acid increased somewhat more rapidly in the serum of the animal receiving pyridoxine in the diet than in the littermate fed a diet without pyridoxine, although the magnitude of change was about the same. Apparently the conversion of linoleic acid to arachidonic acid is possible without the presence of vitamin B₆ in the diet.

² Supported in part by a grant from Corn Products Company, Institute of Nutrition, Argo, Illinois.

³ International Postdoctoral Research Fellow of the National Institutes of Health (P.H.S. FF-264). Present address: Lasarettet, Skelleftea, Sweden.

Manuscript received 2 July 1962.