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Journal of Nutrition Vol. 77 No. 3 July 1962, pp. 343-348
Copyright © 1962 by American Society for Nutrition
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Studies in Relation to Lipid Metabolism in Man

I. Polyunsaturated Fatty Acids in Relation to Total Fatty Acids in Male and Female Patients of Different Ages, with Complaints of Angina Pectoris1, 2,

G. Pol, L. M. Dalderup and E. A. M. Meyknecht

Netherlands Institute of Nutrition, Wageningen, Holland

An inverse relationship between the serum total fatty acid content and its relative amounts of polyunsaturated fatty acids was demonstrated in patients with anginal complaints. The decrease in poly-unsaturated fatty acid content with higher total fatty acid levels was sharper in men than in women.

With increasing age there was a decrease in polyunsaturated fatty acids found at a certain total fatty acid level. This was true both for men and women.

Apart from the other polyenes, triene did not vary in harmony with the total polyunsaturated fatty acid content. Therefore, the triene/tetraene ratio increased in correlation with the total fatty acid content.

Alterations in polyunsaturated fatty acid composition in relation to serum polyunsaturated fatty acid content were not statistically significant, the composition being almost the same in men and women.

No differences were found between the patients who had had a myocardial infarction previously and those with anginal complaints only.

1 This work was sponsored by the Productschap voor Zuivel.

2 This study, the results of which were only partly worked up in this paper, was a cooperative one, the clinical work being carried out in the hospital of St. Antoniushove, and the chemical work described in the Netherlands Institute of Nutrition.

Manuscript received 22 January 1962.




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