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Journal of Nutrition Vol. 77 No. 3 July 1962, pp. 299-302
Copyright © 1962 by American Society for Nutrition
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The Curative Effect of a High-Calcium Diet on Senile Osteoporosis

J. F. McClendon, Jenifer Jowsey, J. Gershon-Cohen and William C. Foster

X-ray Department, Albert Einstein Medical Center and Misericordia Hospital, Philadelphia, Pennsylvania

Long-term calcium-deficient diets produced osteoporosis in rats, which was characterized by chemical, roentgenographic and microradiographic studies. A normally mineralized skeleton could be restored by feeding a dietary supplement of simulated nonprotein milk solids containing calcium phosphate. These observations suggest that osteoporosis in humans may result from long-term negative calcium balance and that calcium phosphate supplements in the diet may be used to cure the condition.

Manuscript received 20 November 1961.




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