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Liver Iron Depletion Without Copper Loss in Swine Fed Excess Zinc¹

Departments of Animal Diseases and Animal Husbandry, Georgia Coastal Plain Experiment Station, Tifton, Georgia

Weanling pigs were placed on experiment to study the influence of high levels of dietary zinc on liver iron, copper, and zinc.

Zinc levels of 0.2 and 0.4% in a soybean meal diet produced neither signs of a marked toxicosis nor an adverse effect on growth or feed consumption.

Evidence was obtained demonstrating that 0.4% of zinc in the diet of swine results in a significant reduction in liver iron without a concomitant loss of liver copper. On the other hand, although 0.2% of zinc in the diet caused a significant increase of liver zinc, the iron content in the liver was not decreased.

² Present address: Department of Nutrition, University Hospitals, University of Iowa, Iowa City, Iowa.

Manuscript received 8 January 1962.