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Journal of Nutrition Vol. 76 No. 2 February 1962, pp. 207-209
Copyright © 1962 by American Society for Nutrition
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Distribution of Serum Proteins in Biotin-Deficient Rats

Krishna Sudha Rastogi1

Indian Institute for Biochemistry and Experimental Medicine Calcutta, India

Different fractions of serum proteins were determined by paper electrophoresis in biotin-deficient and pair-fed normal rats. Total serum protein was significantly low in the deficient animals. There was a significant decrease in albumin and ß-globulin with no significant change in {alpha}1-, {alpha}2- and {gamma}-globulin fractions in the serum of biotindeficient rats when compared with pair-fed normal controls.

1 National Research Fellow, Government of India (1957–60). Present address: Department of Physiology, Charles H. Best Institute, University of Toronto, Toronto, Canada.

Manuscript received 12 September 1961.




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