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The Mineral Requirements of the Dog1

III. The Magnesium Requirement

G. E. Bunce2, K. J. Jenkins and P. H. Phillips

Department of Biochemistry, University of Wisconsin, Madison, Wisconsin

The minimal magnesium requirement of the weanling dog fed a semipurified diet was found to be approximately 140 ppm (dry weight basis).

Mineralized lesions were observed in the thoracic aorta of the animals fed the low magnesium. Upon analysis, the mineral was observed to consist largely of calcium and phosphorus. The amount of mineral accumulation in the aorta appeared to be a function of the magnesium content and duration of intake of the diet.

An elevation of blood serum inorganic phosphorus and a depression of serum calcium and magnesium appeared in the lowmagnesium-fed (80 ppm) weanling dog, but no change in aortic magnesium content could be detected.


1 Published with the approval of the Director of Wisconsin Agricultural Experiment Station. Supported in part by the National Dairy Council, Chicago. The crystalline vitamins were kindly provided by Merck, Sharp and Dohme Research Laboratories, Rahway, New Jersey.

2 Present address: U. S. Army Medical Research and Nutrition Laboratory, Fitzsimons General Hospital, Denver 30, Colorado.

Manuscript received 14 July 1961.





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