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Metabolic Patterns in Preadolescent Children

VI. Vitamin B₁₂ Intake and Urinary Excretion¹

Human Nutrition Research Division, United States Department of Agriculture, Washington, D. C.

The vitamin B₁₂ content was determined for each of 6 controlled diets used in a series of metabolic studies with a total of 23 healthy 7- to 9-year-old girls. Urinary vitamin B₁₂ excretions were determined for 11 girls receiving two of these diets that were low in protein.

Diets with a daily average of 48 to 88 gm of total protein (about 65% from animal sources) contained from 3.9 to 4.5 µg of vitamin B₁₂ per day. Diets of lower protein content with a daily average of 18 and 22 gm of total protein (about 40% from animal sources) contained 0.7 and 1.1 µg of vitamin B₁₂ per day, respectively.

The urinary excretion of vitamin B₁₂ for the girls receiving low-protein diets was 9% of the dietary intake at the initiation of the controlled diet phase of the study and from 3 to 4% in latter phases.

Diets, made up of ordinary foods patterned to meet the Food and Nutrition Board's recommended allowances for children 7 to 9 years of age, supplied about 4 µg of vitamin B₁₂ daily.

Manuscript received 20 July 1961.