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Isolation and Nature of an Unidentified Growth Factor(s) in Condensed Fish Solubles^1,2,

Department of Animal Industry and Veterinary Science, University of Arkansas, Fayetteville, Arkansas

Both inorganic and organic compounds were involved in the growth response that was observed when chicks were fed diets containing condensed fish solubles. It appeared that the total growth response observed was due to both an inorganic and organic compound(s). The necessary inorganic constituents included copper and molybdenum.

The growth promoting substance was extremely stable and completely dialyzable across a cellophane membrane. Considerable concentration of the factor was affected by dialysis followed by precipitation with methanol.

² Portion of a thesis presented by the senior author in partial fulfillment of the requirements for the degree of Master of Science at the University of Arkansas.

³ Present address: Oklahoma State University, Stillwater, Oklahoma.

Manuscript received 24 March 1961.