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Vitamin E Saturation Test in Coccidiosis-Infected Rabbits^1,2,

Department of Biochemistry, University of Arkansas Medical Center, Little Rock, Arkansas

1. Rabbits infected with Eimeria stiedae and noninfected rabbits received repeated oral or parenteral administrations of vitamin E. Serum, feces and liver were analyzed for vitamin E.

2. The earlier observation that hepatic coccidiosis leads to low vitamin E reserves of the host animal has been confirmed.

3. The results exclude intestinal malabsorption of the vitamin as the cause for the low tissue vitamin E levels in the in-infected rabbits.

4. Other possible mechanisms for the effect of coccidiosis on the vitamin E reserves of the host are discussed.

² Presented in part at the annual meeting of the American Institute of Nutrition, Chicago, 1960.

Manuscript received 20 March 1961.