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Journal of Nutrition Vol. 74 No. 4 August 1961, pp. 345-351
Copyright © 1961 by American Society for Nutrition
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Metabolic Patterns in Preadolescent Children

V. Intake and Urinary Excretion of Pantothenic Acid and of Folic Acid1

June K. Pace, Larue B. Stier, Doris D. Taylor and Patricia S. Goodman

Human Nutrition Research Division, United States Department of Agriculture, Washington, D. C.

Pantothenic acid and folic acid content of food and urine was determined for 35 girls, 7 to 9 years of age, maintained with controlled diets. Three series of metabolic studies were made.

Pantothenic acid intakes in the three studies averaged 4.49, 5.00, and 2.79 mg per child per day; urinary excretions averaged 2.85, 1.71, and 1.31 mg per day, respectively. In general, with the higher intakes of pantothenic acid the urinary excretion tended to be higher.

With an increased protein intake there was an increased pantothenic acid intake since many of the foods high in pantothenic acid are likely to contain considerable protein.

Pantothenic acid excretion for the girls in these studies could not be related to body size.

Folic acid intake in the three studies averaged 98, 80, and 52 µg per child per day; urinary excretion averaged 1.24, 1.13, and 1.41 µg per day, respectively.

Excretion of folic acid in the urine accounted for less than 3% of the intake. The amount excreted did not show relationship to folic acid intake, pantothenic acid intake, protein intake, or body weight.

Diets, made up of ordinary foods planned to meet the National Research Council's recommended allowances of well known nutrients for children 7 to 9 years of age, supplied from 4 to 5 mg of pantothenic acid and from 80 to 100 µg of folic acid per day.

1 This study was a phase of the Southern Regional Research Project, Requirements and Utilization of Selected Nutrients by Preadolescent Children, supported in part by funds appropriated to the U. S. Department of Agriculture under the Research and Marketing Act of 1946, and the Hatch Act, as amended. The Human Nutrition Research Division of the Agricultural Research Service was a cooperator in this project.

Manuscript received 6 February 1961.




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