QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Purchase Article View Shopping Cart Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Nimni, M. E. Articles by Troparevsky, A. Search for Related Content PubMed Articles by Nimni, M. E. Articles by Troparevsky, A.

Effect of Short-Term Feeding of Fish Oils and of Antioxidants on Plasma and Liver Cholesterol in the Rat

Departmento de Biología y Medicina, Comisión Nacional de Energía Atómica, Buenos Aires, Argentina

The addition of different fish oils to basal carbohydrate or fat diets induced hypocholesterolemia in the rat. On the other hand these same diets increased the liver cholesterol levels. The observed hypocholesterolemia is a consequence of a decrease in the esterified fraction, whereas liver cholesterol increase was mainly due to an accumulation of free cholesterol.

The addition of N,N¹-diphenyl-'-phenylenediamine and 1,2-dihydro-2,2,4-trimethyl-6-ethoxyquinoline to high fat diets supplemented with 20% of shad oil tended to reverse the effects produced by the fish oil. It decreased the degree of hypocholesterolemia and the accumulation of liver cholesterol. Butyl-4-methoxyphenol, another antioxidant studied, was ineffective in this respect.

Manuscript received 29 August 1960.