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A New Analogue of Vitamin B₁₂ More Efficient for Growth Response of Rats

Laboratori Ricerche Microbiologia e Chemioterapia, Società Farmitalia, Milan, Italy

The growth action of a new analogue of vitamin B₁₂ isolated in our laboratory has been studied in rats fed a vitamin B₁₂-deficient soybean-base diet.

The analogue promoted much more efficient body weight gain in rats than vitamin B₁₂.

Diet intake, hematological picture and weight, histological aspects and vitamin content of some organs have also been considered: both substances modified behavior to an almost similar mode and degree.

It was not at once possible to deduce which mechanism of action makes the analogue more active than vitamin B₁₂.