Journal of Nutrition

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Journal of Nutrition Vol. 72 No. 2 October 1960, pp. 196-202
Copyright © 1960 by American Society for Nutrition
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Effects of Purified Linoleic Ester on Cholesterol in the Rat1

F. W. Quackenbush and Mary D. Pawlowski2

Department of Biochemistry, Purdue University, Lafayette, Indiana

Linoleic ester of high purity was shown to lower markedly the plasma cholesterol level of hypercholesteremic cholesterol-fed rats. It also lowered liver cholesterol of the rats receiving a low-fat diet (2%) but not those fed a high-fat diet (10% of linolate and 10% of hydrogenated coconut oil).

1 Journal Paper no. 1560 of the Purdue University Agricultural Experiment Station, Lafayette, Indiana.

2 Present address: Worchester Foundation for Experimental Biology, Shrewsbury, Massachusetts.

Manuscript received 20 January 1960.




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