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Journal of Nutrition Vol. 72 No. 1 September 1960, pp. 53-65
Copyright © 1960 by American Society for Nutrition
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Cardiac Lesions and Related Findings in Young Vitamin B6-Deficient Rats1

Joseph Seronde, Jr.

Laboratory of Comparative Pathology, Stow, Massachusetts

Rats receiving a pyridoxine-deficient diet at weaning survived about two months, then died, showing cardiac and renal hypertrophy, myocardial lesions, cardiac dilatation, atrial thrombi and hydrothorax in a significant number of cases. The interrelationships of these lesions and their possible meaning is discussed.

1 This investigation was supported in part by a research grant H-3510 from the National Heart Institute, Public Health Service.

Manuscript received 2 May 1960.




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