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Journal of Nutrition Vol. 71 No. 2 June 1960, pp. 122-124
Copyright © 1960 by American Society for Nutrition
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The Absence of Hemorrhagenic Compounds in Irradiated Beef1

M. S. Mameesh and B. Connor Johnson

Division of Animal Nutrition, University of Illinois, Urbana

Studies of the nature of the hemorrhagic syndrome observed in weanling male rats fed irradiated beef indicated that the syndrome was caused by a lack of vitamin K and not by any hypoprothrombinemic factor in irradiated beef. This conclusion was based on the observations that: (1) when the level of irradiated beef in the diet was increased, the incidence and severity of hemorrhages decreased; and (2) the vitamin K requirement of coprophagy-prevented rats fed a diet high in irradiated beef was found to be the same as that reported for similar rats fed a purified diet.

1 These studies were supported in part under contract no. Da-49-007-MD-544, with the Office of the Surgeon General, Department of the Army. The opinions expressed in this publication are those of the authors and not necessarily those of the Department of the Army.

Manuscript received 2 January 1960.




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