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The Effect of Non-Specific Nutrients on Absorption and Catabolism of Essential Amino Acids by a Bacterium

Edmond C.-c. Ku, Kendall W. King and R. W. Engel

Departments of Biochemistry and Nutrition and of Biology, Virginia Polytechnic Institute, Blacksburg1

A mutant strain of Escherichia coli, known to require threonine, methionine and leucine, was examined with regard to nitrogen balance between cells and medium under conditions of nitrogen starvation and nitrogen-excess and of energy (glucose) starvation and excess. Each of the three amino acids studied was metabolized in a characteristic manner.

1 Supported by the Polychemicals Department, E. I. du Pont de Nemours and Company, Wilmington, Delaware.

Manuscript received 25 September 1959.




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