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The Requirement of the Baby Pig for Orally Administered Iron¹

Michigan State University, East Lansing

Forty-five baby pigs were fed a synthetic milk diet (25 parts of iron per million parts of solids) supplemented with zero, 10, 50, 100 or 200 parts of ferrous iron (FeSO₄·7H₂O) per million parts of solids. The following observations were made at weekly or biweekly intervals: weight gain, hemoglobin concentration, hematocrit, erythrocyte count, reticulocyte count, leucocyte count, total serum protein, serum protein electrophoretic pattern, serum iron concentration, unbound iron-binding capacity of serum, total iron-binding capacity of serum and percentage saturation of transferrin with iron. Iron balance studies, bone marrow biopsies and tissue analyses were also performed. Under the specified conditions, 125 ppm of oral iron appear adequate for the baby pig.

² The authors wish to acknowledge the assistance of R. E. Samson and E. D. Purkhiser in feed formulation and animal care, and of R. M. Diener in performing the bone-marrow biopsies.

Manuscript received 22 June 1959.