Journal of Nutrition

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Journal of Nutrition Vol. 70 No. 1 January 1960, pp. 77-80
Copyright © 1960 by American Society for Nutrition
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The Effect of Cold on the Weight, Food Intake and Acetylating Activity of Pantothenic Acid-Deficient Rats1

David A. Vaughan and Lucile N. Vaughan

Arctic Aeromedical Laboratory, APO 731, Seattle, Washington

Weight changes, food intakes and acetylating activities were measured in rats kept at 5° and 25°C while receiving graded levels of calcium pantothenate in their diet.

The cold-induced increment in food intake was uniform at all levels of dietary calcium pantothenate, and it appears that, for growth, rats do not require a higher level of calcium pantothenate in their diet when exposed to 5°C.

In vivo acetylating activity did not appear to be affected by cold exposure, although it was significantly lower in pantothenate-deficient rats.

1 The views expressed are those of the authors and do not necessarily represent official Air Force policy. The experiments were conducted according to the "Rules Regarding Animal Care" as established by the American Medical Association. (AFR 160-94.)

Manuscript received 6 July 1959.




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