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The Antithyrotoxic Factor of Liver

II. Comparative Activities of Defatted Liver Residue and Various Fats

Nutrition Research Department, Abbott Laboratories, North Chicago, Illinois

Unsaturated vegetable fats promoted growth of thyrotoxic rats, an effect which appeared to be directly related to the linoleic acid supplied by the fats. Hydrogenated coconut oil was ineffective and butterfat was marginal. The fat fraction of liver residue was, however, more active than other fats supplying more linoleic acid. The defatted fraction of liver residue promoted growth over and above all levels of fats. Growth stimulation by defatted liver residue and linoleic acid containing fats, or liver fat, appeared to be additive.