Journal of Nutrition Animal Diets/Enrichment Products...

Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
QUICK SEARCH:   [advanced]


     

Journal of Nutrition Vol. 67 No. 4 April 1959, pp. 589-598
Copyright © 1959 by American Society for Nutrition
This Article
Right arrow Full Text (PDF)
Right arrow Purchase Article
Right arrow View Shopping Cart
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Ackerman, C. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ackerman, C. J.

Growth-Promoting Activity of Meat Meal and Certain Tissues in Goitrogen-Fed Rats and Chicks1

C. J. Ackerman

Department of Biochemistry and Nutrition, Virginia Polytechnic Institute, Blacksburg

The effect of meat meal on the growth of rats fed certain goitrogenic agents has been studied. Meat meal at a dietary level of 5% stimulated growth of rats fed thiourea, thiouracil, sulfaguanidine, sulfathiazole, sulfamethazine or sulfapyridine. However, growth approached normal levels only when sulfaguanidine plus meat meal was fed. The thyroid glands of rats fed goitrogen plus meat meal tended to weigh less than those from rats fed only the goitrogen. It appears that there is little correlation between the size of the thyroid gland and growth of the rats.

The growth stimulation from dietary meat meal in sulfaguanidine-fed chickens was not as pronounced as that observed in rats. One or two per cent sulfaguanidine markedly inhibited growth of chickens but thyroid glands were enlarged only slightly. Chicks fed 0.1% thiourea appeared to grow as well or better than those fed 2% sulfaguanidine but thyroid weights were approximately 16 times greater than in the latter.

Assays of various tissues revealed that three of 5 different hog stomach samples were active in promoting growth of rats fed sulfaguanidine. Hog pancreas and hog duodenum and spleen were also active. Two samples of fish preparations stimulated growth but liver, kidney, brain, and hog pyloric section of the stomach were inactive.

1 This work was supported by a grant from the Williams-Waterman fund of Research Corporation. Presented in part at the 21st annual meeting of the American Institute of Nutrition, Chicago, April 18, 1957. Federation Proceedings, 16, part 1, p. 379 (1957). Also presented in part at the 10th Research Conference of the American Meat Institute, Chicago, February 28, 1958.

Manuscript received 14 July 1958.




Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]