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Further Studies on the Difference in Cariogenicity of Two Diets Comparable in Sucrose Content

Department of Physiology, Emory University, Atlanta, Georgia

These experimental studies were conducted in an attempt to determine what factor or factors are responsible for the marked difference in the cariogenicity of two high-sucrose diets, comparable in sucrose content but differing in the concentration of some of the vitamins and minerals.

The compositions of these diets have been varied by the addition, deletion and exchange of some of the various components which were in different concentrations in the two diets. The components studied were magnesium, manganese, iron, sodium, potassium, yeast, yeast and liver extract and the vitamin mixtures.

The results of these experiments indicate that variations in these components did not alter the cariogenicity of these two diets and that further investigation will be necessary to find the factor or factors which are responsible for the marked difference in their cariogenicity.