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The Retention of Fluoride by the Skeleton, Liver, Heart and Kidney as a Function of Dietary Fat Intake in the Rat¹

Department of Chemistry and School of Dentistry, Indiana University, Bloomington

The effect of feeding different dietary fats at a 5 and 20% level in the presence or absence of fluoride has been studied in order to determine if either the amount or type of fat is associated with increased retention of fluoride in the skeleton, liver, heart and kidney in the rat. Increasing the dietary fat from 5 to 20% results in more fluoride retention in the whole carcass, femur and soft tissues when 2 mg of fluoride is fed daily. Neither the dietary fats nor the presence of the fluoride at the levels used in these studies was associated with a decrease in body weight gain.

² Post-Doctorate Fellow. On leave of absence from the University of Mainz, Mainz, Germany.

Manuscript received 9 January 1958.