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Studies on the toxicity of Indigofera Endecaphylla

I. Toxicity for Rabbits

Commonwealth Scientific and Industrial Research Organization Plant and Soils Laboratory, Division of Plant Industry, Brisbane Department of Pathology, Brisbane Hospital. Department of Physiology, University of Queensland, Brisbane, Australia

1. Rabbits fed green leaf, dried leaf or seed of I. endecaphylla develop severe liver damage.

2. ß-Nitropropionic acid could not be detected in the seed though it is present in the leaf.

3. Leaf of two strains of I. endecaphylla each contained twice the amount of ß-nitropropionic acid of the other strain used. This difference had no effect on the liver damage induced by feeding the three strains.

4. Synthetic ß-nitropropionic acid is not toxic to rabbit liver when force fed in amounts comparable to that in the green leaf.

5. It appears that the toxin of Indigofera endecaphylla is not ß-nitropropionic acid.