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The Absorption of Radiolysine by the Chick as Affected by Penicillin Administration

Division of Animal Nutrition, University of Illinois, Urbana

A study has been made of the effect of feeding penicillin on the disappearance of radioactivity from the digestive tract of the chick following an oral dose of C¹⁴-L-lysine. In each of two experiments, antibiotic administration was associated with a decrease in the weight of the small intestine and ceca, and a decrease in the amount of radioactivity recovered from the digestive tract two and one-half and one hour, respectively, after administration of the labelled amino acid. The results imply that absorption was more efficient from the lighter intestinal tract of the penicillin-fed birds than from the heavier tract of the controls.