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The Acceleration of Vitamin E Deficiency in the Chick by Torula Yeast¹

Laboratory of Nutrition and Endocrinology, National Institute of Arthritis and Metabolic Diseases, Public Health Service, U. S. Department of Health, Education, and Welfare, Bethesda, Maryland

New Hampshire chicks were fed purified diets essentially free of vitamin E, Factor 3 and selenium in which amino acids or soy protein were the sources of nitrogen. The addition of 7.5 to 30% of torula yeast to these diets accelerated the development of exudative diathesis. This property was not associated with the lipid component of the yeast. Washing the yeast with water did not remove the activity. An ash of the yeast, however, promoted exudates. The storage of injected -tocopherol was impaired in chicks fed a high torula yeast diet compared with chicks fed a soy protein diet. It appears that the exudate-producing activity is associated with the mineral component of the yeast.

Manuscript received 25 July 1957.