QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Purchase Article View Shopping Cart Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Wasserman, R. H. Articles by Lengemann, F. W. Search for Related Content PubMed PubMed Citation Articles by Wasserman, R. H. Articles by Lengemann, F. W.

Interrelated Effects of L-Lysine and other Dietary Factors on the Gastrointestinal Absorption of Calcium 45 in the Rat and Chick

Medical Division, Oak Ridge Institute of Nuclear Studies, Oak Ridge, Tennessee^,3

1. Singly administered L-lysine and vitamin D promoted Ca⁴⁵ absorption in the vitamin D-deficient rat. The combined effect of L-lysine and vitamin D was about the sum of the effects of the individual components. L-Lysine and lactose singly increased Ca⁴⁵ absorption in the normal rat, and their combined effect was also additive.

2. In contrast to the rat, L-lysine, L-arginine, and skim milk powder did not increase Ca⁴⁵ absorption in the rachitic chick. Treatment of the rachitic chick with vitamin D resulted in nearly complete absorption of Ca⁴⁵ in this species. For this reason, the combined effect of other substances with vitamin D could not be evaluated.

3. Proportionally more of the absorbed Ca⁴⁵ was found in the femurs of the vitamin D-supplemented rat than in the vitamin D-deficient rat. Vitamin D had no apparent effect on the deposition of absorbed Ca⁴⁵ in the tibias of the rachitic chick.

² Summer Participant at the Oak Ridge Institute of Nuclear Studies, Oak Ridge, Tennessee, for 1956. Permanent address: Department of Chemistry, University of Tennessee Medical School, Memphis, Tennessee.

³ Under contract with the United States Atomic Energy Commission.

Manuscript received 17 January 1957.