Journal of Nutrition OpenSOurce Diets- www.ResearchDiets.com

Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
QUICK SEARCH:   [advanced]


     

Journal of Nutrition Vol. 60 No. 1 September 1956, pp. 65-74
Copyright © 1956 by American Society for Nutrition
This Article
Right arrow Full Text (PDF)
Right arrow Purchase Article
Right arrow View Shopping Cart
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Okey, R.
Right arrow Articles by Lyman, M. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Okey, R.
Right arrow Articles by Lyman, M. M.

Food Intake and Estrogenic Hormone Effects on Serum and Tissue Cholesterol1,2,

Ruth Okey and Marian M. Lyman

Department of Home Economics, University of California, Berkeley

An ad libitum and a pair-feeding study are reported for castrated male rats fed 1% cholesterol with 15 and with 30% protein. In each case one castrate group was treated with estradiol benzoate.

Food intakes of the hormone-dosed castrates were reduced one third to one fourth as compared with ad libitum controls, intact and castrate, respectively. However, when undosed castrates were pair-fed to those dosed with hormone, they gained approximately twice as much.

The ad libitum intact controls showed the usual higher liver cholesterol with the 15 than with the 30% protein diet. Variation in liver cholesterol with protein content of the diet was less in castrates than in controls.

In the undosed rats restricted as to food intake, serum cholesterols were higher and liver cholesterols lower than in the ad libitum-fed rats. The increase in serum cholesterol with restriction of food intake was greater in the rats fed 30% protein.

Serum cholesterols were very high and adrenal cholesterols were increased in the hormone-dosed rats, but liver cholesterols for both diet groups were within the ranges of those of the intact controls fed 15% protein. Data are discussed in terms of relationship of food and cholesterol intake to serum and liver cholesterol.

1 Supported in part by grant-in-aid H-1013, National Heart Institute, U. S. Department of Health, Education and Welfare and by funds appropriated under the Research and Marketing Act of 1946 as part of Western Regional Experiment Station Project W-4.

2 Presented at the Atlantic City Meeting of the Federation of Societies for Experimental Biology, April 1956.

Manuscript received 5 March 1956.




Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]