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The Influence of Chlortetracycline and Vitamin B12, Alone and in Combination, on Nitrogen Utilization by Growing Swine1

R. J. Meade and R. M. Forbes

Department of Animal Husbandry, University of Nebraska, Lincoln ,and Division of Animal Nutrition, University of Illinois, Urbana

Growing barrow pigs weighing from 19.50 to 77.44 kg (mean 43.50 kg) and with metabolic size values of 8.49 to 23.35 (mean 15.64) did not show a significant increase in nitrogen retention when a 14.1% crude protein diet was supplemented with either 22 mg of chlortetracycline, 11 µg of vitamin B12, or a combination of the two, per kilogram of diet.

Highly significant correlations were found between body weight in kilograms raised to the power 0.734 and nitrogen retention within each of the three levels of feed intake used. Highly significant differences in nitrogen retention were demonstrated to exist due to level of feed intake.

Pigs consuming more total feed were able to utilize their nitrogen more efficiently for body gains as evidenced by the highly significant increases in nitrogen retention due to increased level of feed intake.

Neither chlortetracycline nor vitamin B12, nor a combination of the two, exerted a sparing action per se upon the protein requirement of growing swine fed the 14.1% protein diet used in this study.


1 Published with the approval of the Director as Paper no. 726, Journal Series, Nebraska Agricultural Experiment Station. Part of a Thesis submitted by the senior author to the Graduate College, University of Illinois, Urbana, in partial fulfillment of the requirements for the Doctor of Philosophy Degree.

Manuscript received 28 October 1955.





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