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Department of Biochemistry and Nutrition University of Nebraska, Lincoln
Rats fed raw soybean oil meal were found to excrete about 4 time as much indican and to grow at about three-fourths the rate of rats fed autoclaved meal. Addition of crude trypsin powder to the rations equalized the growth rate without affecting indican excretion. Addition of indole to rations markedly increased indican excretion without affecting the growth rate. The feeding of streptomycin greatly depressed indican excretion without affecting the growth rate. Each of the two conditions under study, namely indican excretion and growth inhibition, was produced independently of the other. Therefore, it is concluded that no causal relationship exists between increased indican excretion and the decreased growth rate which result from raw soybean oil meal feeding.
Manuscript received 10 December 1955.