Journal of Nutrition

Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
QUICK SEARCH:   [advanced]


     

Journal of Nutrition Vol. 59 No. 3 July 1956, pp. 425-433
Copyright © 1956 by American Society for Nutrition
This Article
Right arrow Full Text (PDF)
Right arrow Purchase Article
Right arrow View Shopping Cart
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Miller, R. F.
Right arrow Articles by Phillips, P. H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Miller, R. F.
Right arrow Articles by Phillips, P. H.

The Effect of Age on the Level and Metabolism of Fluorine in the Bones of the Fluoridated Rat1,2,

Russell F. Miller3 and Paul H. Phillips

Department of Biochemistry, University of Wisconsin, Madison

An effect of age upon the deposition and retention of femur fluorine has been demonstrated. Fluorine was deposited in greater amounts in the femur of the young rat than in that of the mature rat; however, both the young and mature rat femurs continued to concentrate fluorine progressively with time. Femur fluorine in the rat was mobilized from this bone during periods of low fluorine intake. Again age affected the rate and extent of such femur F- catabolism. The mobilization of femur fluorine of the weanling rat accompanied by an increase in age caused bone changes in the femur which closed a portion of the available fluorine deposition sites to subsequent re-fluoridation.

1 Published with the approval of the Director of Wisconsin Agriculture Experimental Station. Supported in part by a grant from the Aluminum Co. of America, Pittsburgh, Pa., on behalf of itself and Aluminum Laboratories Ltd., American Smelting and Refining Co., Kaiser Aluminum and Chemical Corp., Monsanto Chemical Co., Reynolds Metal Co., Tennessee Valley Anthority, U. S. Steel Corp. of Delaware, and Westvaco, Chemical Division of Food Machinery and Chemical Corp.

2 Submitted in part as a Ph.D. thesis by Russell F. Miller to the Graduate School of the University of Wisconsin.

3 Present address: Department of Biochemistry and Nutrition, Virgini Agricultural Experiment Station, Blacksburg.

Manuscript received 1 December 1955.




Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]