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Journal of Nutrition Vol. 58 No. 2 February 1956, pp. 175-188
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The Effect of Low Temperature and Dietary Calcium upon Magnesium Requirement1

Four Figures

D. M. Hegsted, J. J. Vitale and Helen McGrath

Department of Nutrition, Harvard School of Public Health and Department of Biochemistry, Harvard Medical School, Boston, Massachusetts

Growth studies with weanling albino rats show that the magnesium required per gram of diet to promote equal gains in weight appears to be about 4 times higher at an environmental temperature of 55°F. than at 78°F. Since the maximum rate of gain is less at the lower temperature, the difference in the amount required for maximum gain is about twofold, 25 mg per 100 gm at 78°F. compared to 50 mg per 100 gm at 55°F.

High calcium diets were detrimental at low magnesium intakes. In some experiments high calcium diets apparently accentuate cold injury.


1 Supported in part by grants-in-aid from the National Institute of Arthritis and Metabolism (A-194)C, National Institutes of Health, Public Health Service, Bethesda, Maryland; J. M. Kaplan Fund, Inc., New York; General Mills, Inc., and the Nutrition Foundation, New York.

Manuscript received 19 August 1955.





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