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Journal of Nutrition Vol. 57 No. 3 November 1955, pp. 305-317
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Bone Healing in Lysine-Deficient Rats

Seven Figures

Robert Haggar, Thomas D. Kinney and Nathan Kaufman

Departments of Pathology, Cleveland City Hospital, and Western Rescrve University School of Medicine, Cleveland, Ohio

Retarded epiphyseal growth results from lysine deficiency and starvation, but there is no appreciable interference with the healing of bone.

The effects of lysine deficiency are similar to those that occur with restricted food intake and include steady weight loss, retarded skeletal and visceral growth and atrophy of subcutaneous fat and muscles.

Increasing the dietary lysine from 1 to 3% has no effect on either growth or bone healing.

A method for producing uniform lesions in bone for purposes of making comparative studies of healing has been described.

Manuscript received 1 July 1955.




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