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Michigan State College, East Lansing
Fifty-five baby pigs were used in a triplicated experiment to determine the thiamine requirement. Following a depletionadjustment period on a thiamine-free, synthetic-milk diet, the pigs were individually fed diets containing 0, 0.5, 1.0, 1.5 and 2.0 mg of thiamine per kilogram of solids.
Data on individual growth response and dietary intake are presented. Analysis of the data indicates that the minimum thiamine requirement of the baby pig for optimum growth and feed efficiency approximates 1.5 mg per kilogram of dietary solids (10% fat) intake. External, gross and microscopic lesions were present in all pigs receiving less than 1.0 mg per kilogram of solids. Blood thiamine levels were positively related to dietary thiamine intake. Good gaining ability was rapidly restored to deficient animals which received thiamine injections.
2 The data contained in this paper are a portion of the research and thesis to be presented by the senior author in partial fullfillment of the requirements for the degree of Doctor of Philosophy, School of Graduate Studies, Michigan State College, East Lansing.
3 Departments of Animal Husbandry, Animal Pathology and Agricultural Chemistry, Michigan State College, East Lansing. This work was supported in part by a grant-in-aid from the National Vitamin Foundation, Inc., New York, N. Y. The authors are indebted to Merck and Co., Inc., Rahway, New Jersey, and to Lederle Laboratories Division, Pearl River, N. Y. for the B vitamins used in this experiment.
Manuscript received 21 February 1955.